ISSN 1662-4009 (online)

ey0015.14-4 | Sow during infancy and reap later | ESPEYB15

14.4 Epigenetic correlates of neonatal contact in humans

SR Moore , LM McEwen , J Quirt , A Morin , SM Mah , RG Barr , WT Boyce , MS Kobor

To read the full abstract: Development and Psychopathology 2017;29:1517-1538Work in rodents, already some years ago, showed that epigenetic changes can be transmitted trans generations. This study shows that in humans, the simple act of touching during infancy has lifelong consequences on gene expression through epigenetic changes that sustain for at least 4 years. Children who were distresse...

ey0017.15-8 | (1) | ESPEYB17

15.8. Arginine-stimulated copeptin measurements in the differential diagnosis of diabetes insipidus: A prospective diagnostic study

B Winzeler , N Cesana-Nigro , J Refardt , DR Vogt , C Imber , B Morin , M Popovic , M Steinmetz , CO Sailer , G Szinnai , I Chifu , M Fassnacht , M Christ-Crain

To read the full abstract: Lancet. 2019 Aug 17;394(10198):587–595. doi: 10.1016/S0140-6736(19)31255-3.These authors previously described that the measurement of copeptin, a peptide cleaved in the posterior pituitary from the protein precursor of vasopressin and stable in circulation, is an accurate tool to diagnose diabetes insipidus (DI; vasopressin insufficiency). However, the...